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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TLK1 All Species: 19.09
Human Site: S93 Identified Species: 42
UniProt: Q9UKI8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UKI8 NP_036422.3 766 86700 S93 K A S T N N E S S N H S F G S
Chimpanzee Pan troglodytes XP_001141231 787 89005 S93 K A S T N N E S S N H S F G S
Rhesus Macaque Macaca mulatta XP_001084145 718 81923 G93 S Q G K S I G G R G H K I S D
Dog Lupus familis XP_535959 766 86670 S93 K A S T N N E S S N H S F G S
Cat Felis silvestris
Mouse Mus musculus Q8C0V0 766 86605 S93 K A S T N N E S S N H S F G S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515053 718 81881 G93 S Q G K S I G G R G H K I S D
Chicken Gallus gallus XP_426581 764 86358 S94 K A S T N N E S S N H S F G S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q90ZY6 756 85436 S94 L N N N E C S S H S F G S L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624065 793 90042 N121 R S V A A L E N K K I N E Y F
Nematode Worm Caenorhab. elegans P34314 965 109255 M138 M S E D S I E M R D Y N S G V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39238 688 78131 A93 T G D F L I R A N T K K R Q K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 93.5 99.4 N.A. 98.1 N.A. N.A. 91.5 94.1 N.A. 83.2 N.A. N.A. 46.4 37.9 N.A.
Protein Similarity: 100 97.3 93.7 99.7 N.A. 99.2 N.A. N.A. 92.8 95.8 N.A. 89.4 N.A. N.A. 61.2 50.8 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 N.A. N.A. 6.6 100 N.A. 6.6 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 N.A. N.A. 13.3 100 N.A. 20 N.A. N.A. 33.3 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 51.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 46 0 10 10 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 0 0 0 0 0 10 0 0 0 0 19 % D
% Glu: 0 0 10 0 10 0 64 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 10 0 46 0 10 % F
% Gly: 0 10 19 0 0 0 19 19 0 19 0 10 0 55 10 % G
% His: 0 0 0 0 0 0 0 0 10 0 64 0 0 0 0 % H
% Ile: 0 0 0 0 0 37 0 0 0 0 10 0 19 0 0 % I
% Lys: 46 0 0 19 0 0 0 0 10 10 10 28 0 0 10 % K
% Leu: 10 0 0 0 10 10 0 0 0 0 0 0 0 10 0 % L
% Met: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 10 10 10 46 46 0 10 10 46 0 19 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 19 0 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 10 0 0 0 0 0 10 0 28 0 0 0 10 0 0 % R
% Ser: 19 19 46 0 28 0 10 55 46 10 0 46 19 19 46 % S
% Thr: 10 0 0 46 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _